Transcriptional features of multiple myeloma patients with chromosome 1q gain
نویسندگان
چکیده
منابع مشابه
Getting a Clue from 1q: Gain of Chromosome 1q in Cancer
Cytogenetic abnormalities including the gain and loss of chromosomes play an important role in oncogenesis. Aberrations involving chromosome 1 are one of the most common anomalies reported among human neoplasms and have been observed in both solid tumors and hematological malignancies. This review highlights the prognostic import of cytogenetic abnormalities involving 1q in childhood cancers an...
متن کاملClinicopathological features and management of Pakistani patients with multiple myeloma.
OBJECTIVE Purpose of the study was to evaluate the clinicopathological features of multiple myeloma in Pakistan and to study the influence of therapeutic management in these cases. METHODS We retrospectively analyzed 99 newly diagnosed patients with multiple myeloma seen from 1988 to 1996. Diagnostic criteria included bone marrow plasmacytosis, monoclonal gammopathy in serum or urine and radi...
متن کامل[Clinical features and survival of Chilean patients with multiple myeloma].
BACKGROUND Mortality rate records are the only data available in Chile about the prognosis of patients with multiple myeloma (MM). AIM To characterize clinical features, survival rate and factors related to mortality in cases with MM treated in six large medical centers in Chile. MATERIAL AND METHOD Retrospective analysis of demographic data, clinical features and survival rate records of p...
متن کاملTreatment of Multiple Myeloma
Les traitements classiques de myelome multiple et les schemas differents proposes ont ete mis en revue. La poly chimiotherapie de la maladie avec une com-binaison de cyclophosphamide, B.C.N.U. Alkeran, Perdnisone et Vincristine a donnee une meilleur Resultat ceci surtout dans les formes graves et rapidement progressive de la maladie. D'autres sehemas therapeutiques sont en cours.
متن کاملRole of Suppressed Immunoglobulins in Outcome of Patients With Multiple Myeloma
Introduction: Multiple myeloma (MM) is typically presented with abundant monoclonal secretion of one type of immunoglobulin. The other classes of immunoglobulins, which are uninvolved and not secreted by malignant plasma cells, could be decreased. A number of previous studies reported the effect of suppression of uninvolved immunoglobulins on the outcome of patients with myeloma. However, its e...
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ژورنال
عنوان ژورنال: Leukemia
سال: 2007
ISSN: 0887-6924,1476-5551
DOI: 10.1038/sj.leu.2404616